The drug "Betagestin" from dizziness. "Betagistin": instructions for use, price, reviews
How does the drug "Betagistin" (tablets) work? Instructions for use, reviews, descriptions and properties of this medication will be provided below. In addition, we will tell you about the purpose of this drug, how much it costs, whether it has side effects and contraindications.
Composition, description and form
The form of release of this drug is one - a pill. However, they are produced with different amounts of active substance:
- Ploskotsilindrichesky white tablets of the round form with a labeling of a dose of an active component (betagistina dihydrochloride) - 8 mg.
- Oblong and biconvex tablets with rounded edges with a labeling dose of the active ingredient (betagistin dihydrochloride) - 16 or 24 mg.
As auxiliary ingredients, these forms contain sodium lauryl sulfate, sodium croscarmellose, microcrystalline cellulose, magnesium stearate and citric acid.
Pharmacological action of the drug
What is a "Betagistin" medication? Instructions for use (the price of this medication is indicated below) reports that this drug is an analog of histamine, which was created synthetically.
The active ingredient in the tablets is able to use histamine H-3 and H-1 receptors (strong and weak antagonists) of the central nervous system (i.e. receptors of the vestibular nuclei and inner ear).
After taking the medicine, it immediately affectson the bloodstream, promoting the stimulation of microcirculation and permeability of the capillaries of the inner ear. Also, the active component of this drug is able to stabilize the pressure of the endolymph in the cochlea.
Due to the fact that "Betagistin" is aan inhibitor of the H-3 receptors of the nuclei of the vestibular system, it exerts a pronounced effect on the CNS. Thus, the drug in question stabilizes the transmission (neuronal) in the neurons of the vestibular nucleus.
With proper medication, he is able torather quickly eliminate the signs of vestibular vertigo. The exposure time of the active ingredient of this drug is from a few minutes to one day.
Regular intake of the drug under the supervision of a doctor reduces the incidence of dizziness, reduces ringing and tinnitus, and restores hearing when it worsens.
This medication does not have sedative effects and does not cause disturbances in coordination.
The drug "Betagestin" from dizziness is absorbed quickly and completely. Its peak concentrations in the blood are reached approximately 65 minutes after taking on an empty stomach.
The active substance of the drug binds to proteins by less than 5%.
The drug is excreted by metabolizing up toinactive metabolites - demethylbetahistine and 2-pyridylacetic acid. Practically complete excretion of the drug occurs during the day through the kidneys (about 90%). As for the remaining 10%, they are excreted through the intestine.
Indications for use
Preparation "Betagestin" against dizzinessis prescribed to patients very often. In addition, the drug is used to treat Meniere's syndrome, as well as to eliminate tinnitus, nausea, partial hearing loss and impaired coordination.
It should be specially noted that Meniere's syndromemanifested in the form of auditory and vestibular disorders, which had not previously been observed in humans. It can also occur as an acute stroke. Meniere's syndrome has a high probability of frequent relapses.
Contraindications for use
Now you know the purpose for whichpreparation "Betagestin". From dizziness, he saves very well. However, this medication has contraindications. It can not be administered to people with pheochromocytoma.
In view of the fact that this medication representsa synthetic analogue of histamine, its use can contribute to the release of catecholamines, which in turn leads to severe hypertension.
It should also be noted that taking tablets"Betagistin" is contraindicated in patients with increased sensitivity to the active ingredient or to any other excipients that make up the drug.
The drug "Betagestin" against dizziness should be taken strictly in accordance with the attached instructions.
- Dosage for adult patients.
Tablets "Betagistin" is prescribed in a dosage of 8 or16 mg three times a day (at the beginning of treatment) with or after food. The maintenance dose of the drug varies between 24-48 mg per day (at the discretion of the doctor).
The daily dosage of the drug should not be higher48 mg. It is adjusted taking into account all the individual characteristics of the patient. Sometimes the improvement of his condition can be observed only after a few weeks.
- Treatment of people with cardiac, renal and hepatic insufficiency.
For patients with such diagnoses, the preparation "Betagistin" can be prescribed only after a medical examination.
- Treatment of the elderly.
In the elderly, the drug must be prescribedwith extreme caution. This is due to the fact that in this group of patients there is a huge chance of developing side effects from the body on the auxiliary and active substances that are part of the tablets.
- Treatment of children and adolescents.
Preparation "Betagestin" from dizziness is not prescribed for children and adolescents (less than 18 years). This is due to the lack of information on the effectiveness and safety of the drug.
Cases of overdose
With an overdose of Betagistin, some patients may experience symptoms in the form of nausea, headache, abdominal pain and drowsiness (with a dose of up to 640 mg).
Also, patients can complain of convulsions, vomiting, dyspepsia and ataxia.
More serious complications include cardiovascular and pulmonary complications (observed with deliberate overdose).
Treatment is gastric lavage for 60 minutes after ingestion.
Not all patients taking the drug "Betagestin", may experience discomfort.
Doctors report that the manifestation of adverse reactionswhen taking any medication can mean the patient's adaptation to a new medicine. In this regard, before canceling the drug should always consult with a doctor.
Common side effects from taking "Betagistin" are noted in one out of ten patients. The list of the most common unwanted effects includes such symptoms as:
- upset stomach (usually occurs when taking the medication before meals);
- general poor health;
- discomfort or bloating;
- headaches (you can take painkillers, but only after a preliminary consultation with a specialist);
- allergic reactions to the skin in the form of itching and rash (should take an antihistamine or lubricate the problem areas moisturizer).
If these recommendations do not help to eliminate side effects, the patient should consult a doctor.
Price of medicinal product
The price of tablets "Betagistin" may be different andDepend on the amount of medicine in the package. The drug in a dosage of 24 mg can be purchased for 60-65 rubles. Many patients believe that this is a fairly low cost of the drug.
Reviews about the medicine
Reviews about the drug "Betagistin" areambiguous character. Some patients with chronic diseases of SSS take the pill regularly. However, not always they eliminate headaches and dizziness.
Both negative and positive reviews about this medicine indicate that it requires special application.
Thus, with some violations, the drug "Betagistin" can quickly restore the patient's health, and in others, on the contrary, do not have the expected effect, but only reduce the manifestation of symptoms.